Direct catalytic cross-coupling of alkenyllithium compounds† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03117b

Direct catalytic cross-coupling of alkenyllithium compounds.

A catalytic method for the direct cross-coupling of alkenyllithium reagents with aryl and alkenyl halides is described. The use of a catalyst comprising Pd2(dba)3/XPhos allows for the stereoselective preparation of a wide variety of substituted alkenes in high yields under mild conditions. In addition (1-ethoxyvinyl)lithium can be efficiently converted into substituted vinyl ethers which, after...

Ruthenium(ii)-catalyzed olefination via carbonyl reductive cross-coupling† †Electronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c7sc04207h

Natural availability of carbonyl groups offers reductive carbonyl coupling tremendous synthetic potential for efficient olefin synthesis, yet the catalytic carbonyl cross-coupling remains largely elusive. We report herein such a reaction, mediated by hydrazine under ruthenium(ii) catalysis. This method enables facile and selective cross-couplings of two unsymmetrical carbonyl compounds in eithe...

Flow chemistry as a discovery tool to access sp2–sp3 cross-coupling reactions via diazo compounds† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03072a Click here for additional data file.

Copper(i)-catalyzed sulfonylative Suzuki–Miyaura cross-coupling† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05483h Click here for additional data file.

Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical–radical coupling† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02031g Click here for additional data file.